Sam’s advise is solid. Time machine is a good idea, but not for the data recovery of the RAID, but in case in your attempts to recover the RAID you make changes to the drive config you’d like to undo. You would have an OS snapshot to restore to (albeit painfully). For OS level config data. If they’re stored in controller configs, Time Machine won’t help.
Anytime you make critical changes to MacOS itself (upgrade, config), it’s always worthwhile to have a Time Machine snapshot just in case. Many years back an upgrade went sideways and my MacPro got stuck in a boot loop. Time Machine was my ticket to reverting that.
Having said that, given that we determined that one of your physical disks appears to be missing, you may have a different problem. As a striped RAID 0 volume, unless you get that drive to re-surface, you are out of options for recovery. There’s no redundancy and the data is striped across the four drives, so you’re missing critical parts. Your only hope is that the drive itself hasn’t failed but that it’s simply an unreliable connection that is resolved by reseating it.
What do you have in terms of backups in case the RAID is lost? Hopefully as last resort the Flame Archive on a different volume which you could restore, and then re-cache and re-render everything as needed. Maybe a few hours of just prior to reboot that’s gone gone?
This kind of stuff is everyone’s worst nightmare. You’re on a client job with tight deadline, and suddenly you lose a day (hopefully not more) of work and time to get back to where you were.
We just had that conversation about that Thursday. The reason freelancers and facilities don’t charge the same rate (and shouldn’t) is the resiliency to such failure scenarios among others, and the clients taking calculated risks on that in order to save cost on their end. Though we always do our best to minimize it within reason.
PS: If you have a different M.2 dock available, I’d try to see if that NVME stick comes up outside of your Highpoint controller to troubleshoot if it’s the drive, the socket, or the controller. With that info, if simply reseating doesn’t work but the drive works in a separate dock, you could move it one of the other slots on the controller and hopefully it sees it there, since you only use half the available slots, if I saw the info right.